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Cyclin T1 overexpression induces malignant transformation and tumor growth

Human PTEFb is a protein kinase composed by CDK9 and Cyclin T that controls the elongation phase of RNA Pol II. This complex also affects the activation and differentiation program of lymphoid cells. In this study we found that several head and neck tumor cell lines overexpress PTEFb. We also establ...

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Detalhes bibliográficos
Main Authors: Moiola, Cristian, De Luca, Paola, Gardner, Kevin, Vazquez, Elba, De Siervi, Adriana
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040930/
https://ncbi.nlm.nih.gov/pubmed/20714219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.15.12526
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