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Cyclin T1 overexpression induces malignant transformation and tumor growth
Human PTEFb is a protein kinase composed by CDK9 and Cyclin T that controls the elongation phase of RNA Pol II. This complex also affects the activation and differentiation program of lymphoid cells. In this study we found that several head and neck tumor cell lines overexpress PTEFb. We also establ...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Landes Bioscience
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040930/ https://ncbi.nlm.nih.gov/pubmed/20714219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.15.12526 |
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