BRCA1 Loss Induces GADD153-Mediated Doxorubicin Resistance in Prostate Cancer

BRCA1 plays numerous roles in the regulation of genome integrity and chemoresistance. Although BRCA1 interaction with key proteins involved in DNA repair is well known, its role as a coregulator in the transcriptional response to DNA damage remains poorly understood. In this study, we show that BRCA...

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Veröffentlicht in:Mol Cancer Res
Hauptverfasser: De Luca, Paola, Vazquez, Elba S., Moiola, Cristian P., Zalazar, Florencia, Cotignola, Javier, Gueron, Geraldine, Gardner, Kevin, De Siervi, Adriana
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959536/
https://ncbi.nlm.nih.gov/pubmed/21700680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-11-0155
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