Prostate Tumor Growth Is Impaired by CtBP1 Depletion in High-Fat Diet–Fed Mice

PURPOSE: Clinical and epidemiologic data suggest that obesity is associated with more aggressive forms of prostate cancer, poor prognosis, and increased mortality. C-terminal–binding protein 1 (CtBP1) is a transcription repressor of tumor suppressor genes and is activated by NADH binding. High calor...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Moiola, Cristian P., De Luca, Paola, Zalazar, Florencia, Cotignola, Javier, Rodríguez-Seguí, Santiago A., Gardner, Kevin, Meiss, Roberto, Vallecorsa, Pablo, Pignataro, Omar, Mazza, Osvaldo, Vazquez, Elba S., De Siervi, Adriana
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944435/
https://ncbi.nlm.nih.gov/pubmed/24842953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0322
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