Genetic Evidence for Involvement of Neuronally Expressed S1P(1) Receptor in Nociceptor Sensitization and Inflammatory Pain

Sphingosine-1-phosphate (S1P) is a key regulator of immune response. Immune cells, epithelia and blood cells generate high levels of S1P in inflamed tissue. However, it is not known if S1P acts on the endings of nociceptive neurons, thereby contributing to the generation of inflammatory pain. We fou...

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Detalhes bibliográficos
Main Authors: Mair, Norbert, Benetti, Camilla, Andratsch, Manfred, Leitner, Michael G., Constantin, Cristina E., Camprubí-Robles, Maria, Quarta, Serena, Biasio, Wolfgang, Kuner, Rohini, Gibbins, Ian L., Kress, Michaela, Haberberger, Rainer V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040773/
https://ncbi.nlm.nih.gov/pubmed/21359147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017268
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