Oncostatin M induces heat hypersensitivity by gp130-dependent sensitization of TRPV1 in sensory neurons

Oncostatin M (OSM) is a member of the interleukin-6 cytokine family and regulates eg. gene activation, cell survival, proliferation and differentiation. OSM binds to a receptor complex consisting of the ubiquitously expressed signal transducer gp130 and the ligand binding OSM receptor subunit, which...

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Autori principali: Langeslag, Michiel, Constantin, Cristina E, Andratsch, Manfred, Quarta, Serena, Mair, Norbert, Kress, Michaela
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275481/
https://ncbi.nlm.nih.gov/pubmed/22196363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-102
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