Sphingosine 1-phosphate to p38 signaling via S1P(1) receptor and Gαi/o evokes augmentation of capsaicin-induced ionic currents in mouse sensory neurons

The perception of painful thermal stimuli by sensory neurons is largely mediated by TRPV1. Upon tissue injury or inflammation, S1P is secreted by thrombocytes as part of an inflammatory cocktail, which sensitizes nociceptive neurons towards thermal stimuli. S1P acts on G-protein coupled receptors th...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mol Pain
Asıl Yazarlar: Langeslag, Michiel, Quarta, Serena, Leitner, Michael G, Kress, Michaela, Mair, Norbert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280769/
https://ncbi.nlm.nih.gov/pubmed/25431213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-10-74
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller