Identification of Chloride Channels CLCN3 and CLCN5 Mediating the Excitatory Cl(−) Currents Activated by Sphingosine-1-Phosphate in Sensory Neurons

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid involved in numerous physiological and pathophysiological processes. We have previously reported a S1P-induced nocifensive response in mice by excitation of sensory neurons via activation of an excitatory chloride current. The underlying mole...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Qi, Yanmei, Mair, Norbert, Kummer, Kai K., Leitner, Michael G., Camprubí-Robles, María, Langeslag, Michiel, Kress, Michaela
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811518/
https://ncbi.nlm.nih.gov/pubmed/29479306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00033
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