Sphingosine-1-Phosphate-Induced Nociceptor Excitation and Ongoing Pain Behavior in Mice and Humans Is Largely Mediated by S1P3 Receptor

The biolipid sphingosine-1-phosphate (S1P) is an essential modulator of innate immunity, cell migration, and wound healing. It is released locally upon acute tissue injury from endothelial cells and activated thrombocytes and, therefore, may give rise to acute post-traumatic pain sensation via a yet...

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Pubblicato in:J Neurosci
Autori principali: Camprubí-Robles, María, Mair, Norbert, Andratsch, Manfred, Benetti, Camilla, Beroukas, Dimitra, Rukwied, Roman, Langeslag, Michiel, Proia, Richard L., Schmelz, Martin, Ferrer Montiel, Antonio V., Haberberger, Rainer V., Kress, Michaela
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619173/
https://ncbi.nlm.nih.gov/pubmed/23392686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4479-12.2013
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