Dual vulnerability of tau to calpains and caspase-3 proteolysis under neurotoxic and neurodegenerative conditions

Axonally specific microtubule-associated protein tau is an important component of neurofibrillary tangles found in AD (Alzheimer's disease) and other tauopathy diseases such as CTE (chronic traumatic encephalopathy). Such tau aggregate is found to be hyperphosphorylated and often proteolyticall...

Full description

Saved in:
Bibliographic Details
Main Authors: Cheng Liu, Ming, Kobeissy, Firas, Zheng, Wenrong, Zhang, Zhiqun, Hayes, Ronald L, Wang, Kevin KW
Format: Artigo
Language:Inglês
Published: American Society for Neurochemistry 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040574/
https://ncbi.nlm.nih.gov/pubmed/21359008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20100012
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items