Comparing calpain- and caspase-3-mediated degradation patterns in traumatic brain injury by differential proteome analysis

A major theme of TBI (traumatic brain injury) pathology is the over-activation of multiple proteases. We have previously shown that calpain-1 and -2, and caspase-3 simultaneously produced αII-spectrin BDPs (breakdown products) following TBI. In the present study, we attempted to identify a comprehen...

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Bibliographic Details
Main Authors: Liu, Ming Cheng, Akle, Veronica, Zheng, Wenrong, Dave, Jitendra R., Tortella, Frank C., Hayes, Ronald L., Wang, Kevin K. W.
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2006
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383722/
https://ncbi.nlm.nih.gov/pubmed/16351572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050905
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