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Methylthioinosine Phosphorylase from Pseudomonas aeruginosa. Structure and Annotation of a Novel Enzyme in Quorum Sensing

The PA3004 gene of Pseudomonas aeruginosa PAO1 was originally annotated as a 5’-methylthioadenosine phosphorylase (MTAP). However, the PA3004 encoded protein uses 5’-methylthioinosine (MTI) as a preferred substrate and represents the only known example of a specific MTI phosphorylase (MTIP). MTIP do...

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Dettagli Bibliografici
Autori principali: Guan, Rong, Ho, Meng-Chiao, Almo, Steven C., Schramm, Vern L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040260/
https://ncbi.nlm.nih.gov/pubmed/21197954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101642d
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