Direct method for detecting small quantities of hepatitis B virus DNA in serum and plasma using the polymerase chain reaction.

Serum components inhibit DNA polymerase, thereby obviating direct detection of serum viral DNA sequences by the polymerase chain reaction (PCR). This has necessitated extraction of nucleic acid from sera before performing PCR and has resulted in loss of sensitivity. By adsorbing virus to a solid sur...

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Detaylı Bibliyografya
Asıl Yazarlar: Zeldis, J B, Lee, J H, Mamish, D, Finegold, D J, Sircar, R, Ling, Q, Knudsen, P J, Kuramoto, I K, Mimms, L T
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1989
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC304015/
https://ncbi.nlm.nih.gov/pubmed/2808703
Etiketler: Etiketle
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