Mutations of E3 Ubiquitin Ligase Cbl Family Members Constitute a Novel Common Pathogenic Lesion in Myeloid Malignancies

PURPOSE: Acquired somatic uniparental disomy (UPD) is commonly observed in myelodysplastic syndromes (MDS), myelodysplastic/myeloproliferative neoplasms (MDS/MPN), or secondary acute myelogenous leukemia (sAML) and may point toward genes harboring mutations. Recurrent UPD11q led to identification of...

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Main Authors: Makishima, Hideki, Cazzolli, Heather, Szpurka, Hadrian, Dunbar, Andrew, Tiu, Ramon, Huh, Jungwon, Muramatsu, Hideki, O'Keefe, Christine, Hsi, Eric, Paquette, Ronald L., Kojima, Seiji, List, Alan F., Sekeres, Mikkael A., McDevitt, Michael A., Maciejewski, Jaroslaw P.
格式: Artigo
語言:Inglês
出版: American Society of Clinical Oncology 2009
主題:
Original Reports
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040009/
https://ncbi.nlm.nih.gov/pubmed/19901108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.23.7503
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