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Free radical signalling underlies inhibition of Ca(V)3.2 T-type calcium channels by nitrous oxide in the pain pathway

Nitrous oxide (N(2)O, laughing gas) has been used as an anaesthetic and analgesic for almost two centuries, but its cellular targets remain unclear. Here, we present a molecular mechanism of nitrous oxide's selective inhibition of Ca(V)3.2 low-voltage-activated (T-type) calcium channels in pain...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Orestes, Peihan, Bojadzic, Damir, Lee, JeongHan, Leach, Emily, Salajegheh, Reza, DiGruccio, Michael R, Nelson, Michael T, Todorovic, Slobodan M
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Blackwell Science Inc 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039265/
https://ncbi.nlm.nih.gov/pubmed/21059758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.196220
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