In-vivo silencing of the Ca(v)3.2 T-type calcium channels in sensory neurons alleviates hyperalgesia in rats with streptozocin-induced diabetic neuropathy

Earlier, we showed that streptozocin (STZ)-induced type 1 diabetes in rats leads to the development of painful peripheral diabetic neuropathy (PDN) manifested as thermal hyperalgesia and mechanical allodynia accompanied by significant enhancement of T-type calcium currents (T-currents) and cellular...

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Main Authors: Messinger, Richard B., Naik, Ajit K., Jagodic, Miljen M., Nelson, Michael T., Lee, Woo Yong, Choe, Won Joo, Orestes, Peihan, Latham, Janelle R., Todorovic, Slobodan M., Jevtovic-Todorovic, Vesna
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735619/
https://ncbi.nlm.nih.gov/pubmed/19577366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2009.06.012
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