Selective T-Type Calcium Channel Blockade Alleviates Hyperalgesia in ob/ob Mice

OBJECTIVE: Morbid obesity may be accompanied by diabetes and painful diabetic neuropathy, a poorly understood condition that is manifested by mechanical or thermal allodynia and hyperalgesia. Recent studies have highlighted the importance of T-type calcium channels (T-channels) in peripheral nocicep...

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Detalhes bibliográficos
Main Authors: Latham, Janelle R., Pathirathna, Sriyani, Jagodic, Miljen M., Joo Choe, Won, Levin, Michaela E., Nelson, Michael T., Yong Lee, Woo, Krishnan, Kathiresan, Covey, Douglas F., Todorovic, Slobodan M., Jevtovic-Todorovic, Vesna
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768156/
https://ncbi.nlm.nih.gov/pubmed/19651818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1763
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