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Extraneural manifestations of prion infection in GPI-anchorless transgenic mice

Earlier studies indicated that transgenic (tg) mice engineered to express prion protein (PrP) lacking the glycophosphatidylinositol (GPI(−/−)) membrane anchor formed abnormal proteinase-resistant prion (PrPsc) amyloid deposits in their brains and hearts when infected with the RML strain of murine sc...

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Bibliografske podrobnosti
Main Authors: Lee, Andrew M., Paulsson, Johan F., Cruite, Justin, Andaya, Abegail A., Trifilo, Matthew J., Oldstone, Michael B.A.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039103/
https://ncbi.nlm.nih.gov/pubmed/21227476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.12.012
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