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Discovery of Halopyridines as Quiescent Affinity Labels: Inactivation of Dimethylarginine Dimethylaminohydrolase
In an effort to develop novel covalent modifiers of dimethylarginine dimethylaminohydrolase (DDAH) that are useful for biological applications, a set of “fragment”-sized inhibitors that were identified using a high-throughput screen are tested for time-dependent inhibition. One structural class of i...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3038607/ https://ncbi.nlm.nih.gov/pubmed/21222447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja109207m |
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