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Screening for Dimethylarginine Dimethylaminohydrolase Inhibitors Reveals Ebselen as a Bioavailable Inactivator

[Image: see text] Dimethylarginine dimethylaminohydrolase (DDAH) is an endogenous regulator of nitric oxide production and represents a potential therapeutic target. However, only a small number of biologically useful inhibitors have been reported, and many of these are substrate analogues. To seek...

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Bibliografski detalji
Glavni autori: Linsky, Thomas, Wang, Yun, Fast, Walter
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2011
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171734/
https://ncbi.nlm.nih.gov/pubmed/21927644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml2000824
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