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Screening for Dimethylarginine Dimethylaminohydrolase Inhibitors Reveals Ebselen as a Bioavailable Inactivator
[Image: see text] Dimethylarginine dimethylaminohydrolase (DDAH) is an endogenous regulator of nitric oxide production and represents a potential therapeutic target. However, only a small number of biologically useful inhibitors have been reported, and many of these are substrate analogues. To seek...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical Society
2011
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| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171734/ https://ncbi.nlm.nih.gov/pubmed/21927644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml2000824 |
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