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A Continuous, Fluorescent, High-Throughput Assay for Human Dimethylarginine Dimethylaminohydrolase-1

Inhibitors of human dimethylarginine dimethylaminohydrolase-1 (DDAH-1) are of therapeutic interest for controlling pathological nitric oxide production. Only a limited number of biologically useful inhibitors have been identified, so structurally diverse lead compounds are desired. In contrast with...

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Detalhes bibliográficos
Main Authors: Linsky, Thomas, Fast, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248755/
https://ncbi.nlm.nih.gov/pubmed/21921133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057111417712
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