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Development of a dimethylarginine dimethylaminohydrolase (DDAH) assay for high throughput chemical screening

Nitric oxide (NO) is a potent signaling molecule that needs to be tightly regulated to maintain metabolic and cardiovascular homeostasis. The nitric oxide synthase (NOS)/Dimethylarginine dimethylaminohydrolase (DDAH)/Asymmetric Dimethylarginine (ADMA) pathway is central to this regulation. Specifica...

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Detalhes bibliográficos
Main Authors: Ghebremariam, Yohannes T, Erlanson, Daniel, Yamada, Keisuke, Cooke, John P
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606823/
https://ncbi.nlm.nih.gov/pubmed/22460174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057112441521
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