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A Novel and Potent Inhibitor of Dimethylarginine Dimethylaminohydrolase: A Modulator of Cardiovascular Nitric Oxide

PD 404182 [6H-6-imino-(2,3,4,5-tetrahydropyrimido)[1,2-c]-[1,3]benzothiazine], a heterocyclic iminobenzothiazine derivative, is a member of the Library of Pharmacologically Active Compounds (LOPAC) that is reported to possess antimicrobial and anti-inflammatory properties. In this study, we used bio...

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Detalhes bibliográficos
Main Authors: Ghebremariam, Yohannes T., Erlanson, Daniel A., Cooke, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868884/
https://ncbi.nlm.nih.gov/pubmed/24135074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.206847
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