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On the Mechanism of Dimethylarginine Dimethylaminohydrolase Inactivation by 4-Halopyridines
Small molecules capable of selective covalent protein modification are of significant interest for the development of biological probes and therapeutics. We recently reported that 2-methyl-4-bromopyridine is a quiescent affinity label for the nitric oxide controlling enzyme dimethylarginine dimethyl...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3135753/ https://ncbi.nlm.nih.gov/pubmed/21630706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2033684 |
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