On the Mechanism of Dimethylarginine Dimethylaminohydrolase Inactivation by 4-Halopyridines

Small molecules capable of selective covalent protein modification are of significant interest for the development of biological probes and therapeutics. We recently reported that 2-methyl-4-bromopyridine is a quiescent affinity label for the nitric oxide controlling enzyme dimethylarginine dimethyl...

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Hauptverfasser: Johnson, Corey M., Monzingo, Arthur F., Ke, Zhihong, Yoon, Dae-Wi, Linsky, Thomas W., Guo, Hua, Robertus, Jon D., Fast, Walter
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135753/
https://ncbi.nlm.nih.gov/pubmed/21630706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2033684
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