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Discovery of Halopyridines as Quiescent Affinity Labels: Inactivation of Dimethylarginine Dimethylaminohydrolase

In an effort to develop novel covalent modifiers of dimethylarginine dimethylaminohydrolase (DDAH) that are useful for biological applications, a set of “fragment”-sized inhibitors that were identified using a high-throughput screen are tested for time-dependent inhibition. One structural class of i...

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Autors principals: Johnson, Corey M., Linsky, Thomas W., Yoon, Dae-Wi, Person, Maria D., Fast, Walter
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038607/
https://ncbi.nlm.nih.gov/pubmed/21222447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja109207m
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