β-amyloid impairs axonal BDNF retrograde trafficking

The neurotrophin, brain-derived neurotrophic factor (BDNF), is essential for synaptic function, plasticity and neuronal survival. At the axon terminal, when BDNF binds to its receptor, tropomyosin-related kinase B (TrkB), the signal is propagated along the axon to the cell body, via retrograde trans...

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Detalhes bibliográficos
Main Authors: Poon, Wayne W., Blurton-Jones, Mathew, Tu, Christina H., Feinberg, Leila M., Chabrier, Meredith A., Harris, Joe W., Li Jeon, Noo, Cotman, Carl W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038182/
https://ncbi.nlm.nih.gov/pubmed/19540623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2009.05.012
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