Axonal mRNA in Uninjured and Regenerating Cortical Mammalian Axons

Using a novel microfluidic chamber that allows the isolation of axons without contamination by nonaxonal material, we have for the first time purified mRNA from naive, matured CNS axons, and identified the presence of >300 mRNA transcripts. We demonstrate that the transcripts are axonal in nature...

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Detalhes bibliográficos
Main Authors: Taylor, Anne M., Berchtold, Nicole C., Perreau, Victoria M., Tu, Christina H., Li Jeon, Noo, Cotman, Carl W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632375/
https://ncbi.nlm.nih.gov/pubmed/19369540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6130-08.2009
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