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Axonal mRNA in Uninjured and Regenerating Cortical Mammalian Axons

Using a novel microfluidic chamber that allows the isolation of axons without contamination by nonaxonal material, we have for the first time purified mRNA from naive, matured CNS axons, and identified the presence of >300 mRNA transcripts. We demonstrate that the transcripts are axonal in nature...

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Autors principals: Taylor, Anne M., Berchtold, Nicole C., Perreau, Victoria M., Tu, Christina H., Li Jeon, Noo, Cotman, Carl W.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632375/
https://ncbi.nlm.nih.gov/pubmed/19369540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6130-08.2009
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