β-amyloid impairs axonal BDNF retrograde trafficking

The neurotrophin, brain-derived neurotrophic factor (BDNF), is essential for synaptic function, plasticity and neuronal survival. At the axon terminal, when BDNF binds to its receptor, tropomyosin-related kinase B (TrkB), the signal is propagated along the axon to the cell body, via retrograde trans...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Poon, Wayne W., Blurton-Jones, Mathew, Tu, Christina H., Feinberg, Leila M., Chabrier, Meredith A., Harris, Joe W., Li Jeon, Noo, Cotman, Carl W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038182/
https://ncbi.nlm.nih.gov/pubmed/19540623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2009.05.012
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi