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Structures of APC/C(Cdh1) with substrates identify Cdh1 and Apc10 as the D-box co-receptor
The ubiquitylation of cell cycle regulatory proteins by the large multimeric anaphase promoting complex (APC/C) controls sister chromatid segregation and the exit from mitosis 1,2. Selection of APC/C targets is achieved through recognition of destruction motifs, predominantly the D-box 3 and KEN-box...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3037847/ https://ncbi.nlm.nih.gov/pubmed/21107322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09625 |
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