Structures of APC/C(Cdh1) with substrates identify Cdh1 and Apc10 as the D-box co-receptor

The ubiquitylation of cell cycle regulatory proteins by the large multimeric anaphase promoting complex (APC/C) controls sister chromatid segregation and the exit from mitosis 1,2. Selection of APC/C targets is achieved through recognition of destruction motifs, predominantly the D-box 3 and KEN-box...

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Bibliographic Details
Main Authors:	da Fonseca, Paula C.A., Kong, Eric H., Zhang, Ziguo, Schreiber, Anne, Williams, Mark. A., Morris, Edward P., Barford, David
Format:	Artigo
Language:	Inglês
Published:	2010
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3037847/ https://ncbi.nlm.nih.gov/pubmed/21107322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09625
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Structures of APC/C(Cdh1) with substrates identify Cdh1 and Apc10 as the D-box co-receptor

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