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Insights into Degron Recognition by APC/C Coactivators from the Structure of an Acm1-Cdh1 Complex
The anaphase-promoting complex/cyclosome (APC/C) regulates sister chromatid segregation and the exit from mitosis. Selection of most APC/C substrates is controlled by coactivator subunits (either Cdc20 or Cdh1) that interact with substrate destruction motifs—predominantly the destruction (D) box and...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3690534/ https://ncbi.nlm.nih.gov/pubmed/23707760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.04.024 |
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