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Insights into the cellular mechanism of the yeast ubiquitin ligase APC/C-Cdh1 from the analysis of in vivo degrons

The anaphase-promoting complex/cyclosome (APC/C) controls a variety of cellular processes through its ability to target numerous protein substrates for timely degradation. Substrate selection by this ubiquitin ligase depends on related activator proteins, Cdc20 and Cdh1, which bind and activate the...

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Publicat a:Mol Biol Cell
Autors principals: Arnold, Lea, Höckner, Sebastian, Seufert, Wolfgang
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342022/
https://ncbi.nlm.nih.gov/pubmed/25540434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-09-1342
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