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Substrate Recognition by the Cdh1 Destruction Box Receptor Is a General Requirement for APC/C(Cdh1)-mediated Proteolysis

The anaphase-promoting complex, or cyclosome (APC/C), is a ubiquitin ligase that selectively targets proteins for degradation in mitosis and the G(1) phase and is an important component of the eukaryotic cell cycle control system. How the APC/C specifically recognizes its substrates is not fully und...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Qin, Liang, Guimarães, Dimitrius Santiago P. S. F., Melesse, Michael, Hall, Mark C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957042/
https://ncbi.nlm.nih.gov/pubmed/27226622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.731190
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