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Opposing roles for HIF-1α and HIF-2α in the regulation of angiogenesis by mononuclear phagocytes

Macrophages contribute to tumor growth through the secretion of the proangiogenic molecule vascular endothelial growth factor (VEGF). We previously observed that monocytes treated with the cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) produce a soluble form of the VEGF receptor-...

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Autori principali: Eubank, Tim D., Roda, Julie M., Liu, Haowen, O'Neil, Todd, Marsh, Clay B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037754/
https://ncbi.nlm.nih.gov/pubmed/20952691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-261792
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