Opposing roles for HIF-1α and HIF-2α in the regulation of angiogenesis by mononuclear phagocytes

Macrophages contribute to tumor growth through the secretion of the proangiogenic molecule vascular endothelial growth factor (VEGF). We previously observed that monocytes treated with the cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) produce a soluble form of the VEGF receptor-...

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Bibliographische Detailangaben
Hauptverfasser: Eubank, Tim D., Roda, Julie M., Liu, Haowen, O'Neil, Todd, Marsh, Clay B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2011
Schlagworte:
Vascular Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037754/
https://ncbi.nlm.nih.gov/pubmed/20952691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-261792
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