Opposing roles for HIF-1α and HIF-2α in the regulation of angiogenesis by mononuclear phagocytes

Macrophages contribute to tumor growth through the secretion of the proangiogenic molecule vascular endothelial growth factor (VEGF). We previously observed that monocytes treated with the cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) produce a soluble form of the VEGF receptor-...

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Detalhes bibliográficos
Main Authors: Eubank, Tim D., Roda, Julie M., Liu, Haowen, O'Neil, Todd, Marsh, Clay B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037754/
https://ncbi.nlm.nih.gov/pubmed/20952691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-261792
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