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14-3-3γ Inhibition of MDMX-mediated p21 Turnover Independent of p53
The stability of p21, a cyclin-dependent kinase inhibitor, is highly regulated by various protein molecules through the cell cycle and in response to extracellular signals. One of the p21 regulators is MDMX, which can directly bind to p21 and mediate its proteasomal degradation in an ubiquitination-...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3037625/ https://ncbi.nlm.nih.gov/pubmed/21148311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.190470 |
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