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Translationally optimal codons associate with aggregation-prone sites in proteins

We analyze the relationship between codon usage bias and residue aggregation propensity in the genomes of four model organisms, E. coli, yeast, fly, and mouse, as well as the archaeon Halobacterium species NRC-1. Using the Mantel-Haenszel procedure, we find that translationally optimal codons associ...

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書誌詳細
主要な著者: Lee, Yaelim, Zhou, Tong, Tartaglia, Gian Gaetano, Vendruscolo, Michele, Wilke, Claus O.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037288/
https://ncbi.nlm.nih.gov/pubmed/21046618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201000229
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