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Translationally optimal codons associate with aggregation-prone sites in proteins
We analyze the relationship between codon usage bias and residue aggregation propensity in the genomes of four model organisms, E. coli, yeast, fly, and mouse, as well as the archaeon Halobacterium species NRC-1. Using the Mantel-Haenszel procedure, we find that translationally optimal codons associ...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3037288/ https://ncbi.nlm.nih.gov/pubmed/21046618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201000229 |
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