Polyelectrolyte Complex Optimization for Macrophage Delivery of Redox Enzyme Nanoparticles

BACKGROUND: We posit that cell-mediated drug delivery can improve transport of therapeutic enzymes to the brain and decrease inflammation and neurodegeneration induced during Parkinson’s disease. Our prior work demonstrated that macrophages loaded with nanoformulated catalase (“nanozyme”) protect th...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhao, Yuling, Haney, Matthew J., Klyachko, Natalia L., Li, Shu, Booth, Stephanie L., Higginbotham, Sheila M., Jones, Jocelyn, Zimmerman, Matthew C., Mosley, R. Lee, Kabanov, Alexander V., Gendelman, Howard E., Batrakova, Elena V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037278/
https://ncbi.nlm.nih.gov/pubmed/21182416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.10.129
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