Cell-mediated Transfer of Catalase Nanoparticles from Macrophages to Brain Endothelial and Neural Cells

BACKGROUND: Our laboratories forged the concept of macrophage delivery of protein antioxidants to attenuate neuroinflammation and nigrostriatal degeneration in Parkinson’s disease (PD). Notably, the delivery of the redox enzyme, catalase, incorporated into a polyion complex micelle (“nanozyme”) by b...

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Autores principales: Haney, Matthew J., Zhao, Yuling, Li, Shu, Higginbotham, Sheila M., Booth, Stephanie L., Han, Huai-Yun, Vetro, Joseph A., Mosley, R. Lee, Kabanov, Alexander V., Gendelman, Howard E., Batrakova, Elena V.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166447/
https://ncbi.nlm.nih.gov/pubmed/21449849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.11.32
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