Cell-mediated Transfer of Catalase Nanoparticles from Macrophages to Brain Endothelial and Neural Cells

BACKGROUND: Our laboratories forged the concept of macrophage delivery of protein antioxidants to attenuate neuroinflammation and nigrostriatal degeneration in Parkinson’s disease (PD). Notably, the delivery of the redox enzyme, catalase, incorporated into a polyion complex micelle (“nanozyme”) by b...

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Detalhes bibliográficos
Main Authors: Haney, Matthew J., Zhao, Yuling, Li, Shu, Higginbotham, Sheila M., Booth, Stephanie L., Han, Huai-Yun, Vetro, Joseph A., Mosley, R. Lee, Kabanov, Alexander V., Gendelman, Howard E., Batrakova, Elena V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166447/
https://ncbi.nlm.nih.gov/pubmed/21449849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.11.32
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