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Structures of Mouse SOD1 and Human/Mouse SOD1 Chimeras(†)

Mutations in human copper-zinc superoxide dismutase (SOD1) cause an inherited form of amyotrophic lateral sclerosis (ALS). Inclusions enriched in pathogenic SOD1 accumulate in the spinal cords of transgenic mice expressing these proteins, but endogenous mouse SOD1 is not found as a component of thes...

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Detalhes bibliográficos
Main Authors: Seetharaman, Sai V., Taylor, Alexander B., Holloway, Stephen, Hart, P. John
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037271/
https://ncbi.nlm.nih.gov/pubmed/20727846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.08.014
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