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Crystal Structure of the Yeast Nicotinamidase Pnc1p
The yeast nicotinamidase Pnc1p acts in transcriptional silencing by reducing levels of nicotinamide, an inhibitor of the histone deacetylase Sir2p. The Pnc1p structure was determined at 2.9 Å resolution using MAD and MIRAS phasing methods after inadvertent crystallization during the pursuit of the s...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1931499/ https://ncbi.nlm.nih.gov/pubmed/17382284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2007.01.037 |
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