Integrin-Linked Kinase Overexpression and Its Oncogenic Role in Promoting Tumorigenicity of Hepatocellular Carcinoma

BACKGROUND: Integrin-linked kinase (ILK) was first discovered as an integrin β1-subunit binding protein. It localizes at the focal adhesions and is involved in cytoskeleton remodeling. ILK overexpression and its dysregulated signaling cascades have been reported in many human cancers. Aberrant expre...

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Main Authors: Chan, Jenny, Ko, Frankie Chi Fat, Yeung, Yin-Shan, Ng, Irene Oi-Lin, Yam, Judy Wai Ping
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036736/
https://ncbi.nlm.nih.gov/pubmed/21347395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016984
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