Integrin-Linked Kinase Overexpression and Its Oncogenic Role in Promoting Tumorigenicity of Hepatocellular Carcinoma

BACKGROUND: Integrin-linked kinase (ILK) was first discovered as an integrin β1-subunit binding protein. It localizes at the focal adhesions and is involved in cytoskeleton remodeling. ILK overexpression and its dysregulated signaling cascades have been reported in many human cancers. Aberrant expre...

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Bibliografiske detaljer
Main Authors: Chan, Jenny, Ko, Frankie Chi Fat, Yeung, Yin-Shan, Ng, Irene Oi-Lin, Yam, Judy Wai Ping
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036736/
https://ncbi.nlm.nih.gov/pubmed/21347395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016984
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