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Solution Structure of the Phosphotyrosine Binding (PTB) Domain of Human Tensin2 Protein in Complex with Deleted in Liver Cancer 1 (DLC1) Peptide Reveals a Novel Peptide Binding Mode

The protein deleted in liver cancer 1 (DLC1) interacts with the tensin family of focal adhesion proteins to play a role as a tumor suppressor in a wide spectrum of human cancers. This interaction has been proven to be crucial to the oncogenic inhibitory capacity and focal adhesion localization of DL...

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Detalhes bibliográficos
Main Authors: Chen, Lihong, Liu, Changdong, Ko, Frankie Chi Fat, Xu, Naining, Ng, Irene Oi-lin, Yam, Judy Wai Ping, Zhu, Guang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406694/
https://ncbi.nlm.nih.gov/pubmed/22645138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.360206
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