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Nuclear-Targeted Deleted in Liver Cancer 1 (DLC1) Is Less Efficient in Exerting Its Tumor Suppressive Activity Both In Vitro and In Vivo

BACKGROUND: Deleted in liver cancer 1 (DLC1) serves as an important RhoGTPase activating protein (RhoGAP) protein that terminates active RhoA signaling in human cancers. Increasing evidence has demonstrated that the tumor suppressive activity of DLC1 depends not only on RhoGAP activity, but also rel...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chan, Lo-Kong, Ko, Frankie Chi Fat, Sze, Karen Man-Fong, Ng, Irene Oi-Lin, Yam, Judy Wai Ping
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180446/
https://ncbi.nlm.nih.gov/pubmed/21966542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025547
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