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Deleted in liver cancer 2 (DLC2) suppresses cell transformation by means of inhibition of RhoA activity
The deleted in liver cancer 2 (DLC2) gene, located at chromosome 13q12.3, is a recently identified tumor suppressor gene. The gene is frequently underexpressed in human hepatocellular carcinoma, and its chromosomal region shows frequent deletion. DLC2 encodes a unique RhoGTPase-activating protein (R...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1250229/ https://ncbi.nlm.nih.gov/pubmed/16217026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504501102 |
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