Integrin-Linked Kinase Overexpression and Its Oncogenic Role in Promoting Tumorigenicity of Hepatocellular Carcinoma

BACKGROUND: Integrin-linked kinase (ILK) was first discovered as an integrin β1-subunit binding protein. It localizes at the focal adhesions and is involved in cytoskeleton remodeling. ILK overexpression and its dysregulated signaling cascades have been reported in many human cancers. Aberrant expre...

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Détails bibliographiques
Auteurs principaux: Chan, Jenny, Ko, Frankie Chi Fat, Yeung, Yin-Shan, Ng, Irene Oi-Lin, Yam, Judy Wai Ping
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036736/
https://ncbi.nlm.nih.gov/pubmed/21347395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016984
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