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Mechanosensitivity of Na(v)1.5, a voltage-sensitive sodium channel

The voltage-sensitive sodium channel Na(v)1.5 (encoded by SCN5A) is expressed in electromechanical organs and is mechanosensitive. This study aimed to determine the mechanosensitive transitions of Na(v)1.5 at the molecular level. Na(v)1.5 was expressed in HEK 293 cells and mechanosensitivity was stu...

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Autors principals: Beyder, Arthur, Rae, James L, Bernard, Cheryl, Strege, Peter R, Sachs, Frederick, Farrugia, Gianrico
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036191/
https://ncbi.nlm.nih.gov/pubmed/21041530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.199034
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