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Mechanosensitivity of Na(v)1.5, a voltage-sensitive sodium channel

The voltage-sensitive sodium channel Na(v)1.5 (encoded by SCN5A) is expressed in electromechanical organs and is mechanosensitive. This study aimed to determine the mechanosensitive transitions of Na(v)1.5 at the molecular level. Na(v)1.5 was expressed in HEK 293 cells and mechanosensitivity was stu...

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Detalhes bibliográficos
Main Authors: Beyder, Arthur, Rae, James L, Bernard, Cheryl, Strege, Peter R, Sachs, Frederick, Farrugia, Gianrico
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036191/
https://ncbi.nlm.nih.gov/pubmed/21041530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.199034
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