Synergistic induction of cell death in liver tumor cells by TRAIL and chemotherapeutic drugs via the BH3-only proteins Bim and Bid

Although death receptors and chemotherapeutic drugs activate distinct apoptosis signaling cascades, crosstalk between the extrinsic and intrinsic apoptosis pathway has been recognized as an important amplification mechanism. Best known in this regard is the amplification of the Fas (CD95) signal in...

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Dettagli Bibliografici
Autori principali: Schneider-Jakob, S, Corazza, N, Badmann, A, Sidler, D, Stuber-Roos, R, Keogh, A, Frese, S, Tschan, M, Brunner, T
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035907/
https://ncbi.nlm.nih.gov/pubmed/21368859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.66
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