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TRAIL enhances paracetamol-induced liver sinusoidal endothelial cell death in a Bim- and Bid-dependent manner

Paracetamol (acetaminophen, APAP) is a universally used analgesic and antipyretic agent. Considered safe at therapeutic doses, overdoses cause acute liver damage characterized by centrilobular hepatic necrosis. One of the major clinical problems of paracetamol-induced liver disease is the developmen...

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Detalles Bibliográficos
Main Authors: Badmann, A, Langsch, S, Keogh, A, Brunner, T, Kaufmann, T, Corazza, N
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542621/
https://ncbi.nlm.nih.gov/pubmed/23254290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.185
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